Vasopressin has 30 known drug interactions based on U.S. FDA drug labeling data. 9 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Bupivacaine Hydrochloride, Bupivacaine Hydrochloride And Epinephrine Bitartrate, Chloroprocaine Hydrochloride. Patients taking Vasopressin should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 30
- Major
- 9
- Moderate
- 21
Major (9)
- Vasopressin + Bupivacaine Hydrochloride— Concurrent administration may cause severe, persistent hypertension or cerebrovascular accidents.
- Vasopressin + Bupivacaine Hydrochloride And Epinephrine Bitartrate— Concurrent administration may cause severe, persistent hypertension or cerebrovascular accidents.
- Vasopressin + Chloroprocaine Hydrochloride— Concurrent administration with ergot-type oxytocic drugs may cause severe, persistent hypertension or cerebrovascular ac…
- Vasopressin + Dopamine Hydrochloride— Risk of severe hypertension. Monitor blood pressure.
- Vasopressin + Lidocaine Hydrochloride— Concurrent administration with ergot-type oxytocic drugs may cause severe, persistent hypertension or cerebrovascular ac…
- Vasopressin + Lidocaine Hydrochloride And Epinephrine Bitartrate— Concurrent administration may cause severe, persistent hypertension or cerebrovascular accidents.
- Vasopressin + Mepivacaine Hydrochloride— Concurrent administration with mepivacaine may cause severe, persistent hypertension or cerebrovascular accidents.
- Vasopressin + Methylphenidate Hydrochloride— Possible increases in blood pressure; methylphenidate should be used cautiously with vasopressor agents.
- Vasopressin + Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride And Dextrose Monohydrate— Avoid concomitant use due to increased risk of hyponatremia. If unavoidable, closely monitor serum sodium concentrations…
Moderate (21)
- Vasopressin + Adrenergic Blockers— May increase the effect of vasopressin on mean arterial blood pressure. Hemodynamic monitoring recommended.
- Vasopressin + Chlorpropamide— Suspected of causing SIADH; may increase pressor and antidiuretic effects of vasopressin. Hemodynamic monitoring recomme…
- Vasopressin + Clozapine— Suspected of causing diabetes insipidus; may decrease pressor and antidiuretic effects of vasopressin. Hemodynamic monit…
- Vasopressin + Cyclophosphamide— Suspected of causing SIADH; may increase pressor and antidiuretic effects of vasopressin. Hemodynamic monitoring recomme…
- Vasopressin + Demeclocycline— Suspected of causing diabetes insipidus; may decrease pressor and antidiuretic effects of vasopressin. Hemodynamic monit…
- Vasopressin + Dextrose— Vasopressin may affect fluid and/or electrolyte balance. Monitor blood glucose concentrations, fluid balance, serum elec…
- Vasopressin + Dextrose And Potassium Chloride— May affect fluid and electrolyte balance; monitor serum electrolyte concentrations and acid-base balance.
- Vasopressin + Dextrose Monohydrate— Concomitant use may increase risk of hyponatremia. Avoid use; if unavoidable, closely monitor serum sodium concentration…
- Vasopressin + Enalapril— Suspected of causing SIADH; may increase pressor and antidiuretic effects of vasopressin. Hemodynamic monitoring recomme…
- Vasopressin + Felbamate— Suspected of causing SIADH; may increase pressor and antidiuretic effects of vasopressin. Hemodynamic monitoring recomme…
- Vasopressin + Foscarnet— Suspected of causing diabetes insipidus; may decrease pressor and antidiuretic effects of vasopressin. Hemodynamic monit…
- Vasopressin + Furosemide— Increases the effect of vasopressin on osmolar clearance and urine flow.
- Vasopressin + Haloperidol— Suspected of causing SIADH; may increase pressor and antidiuretic effects of vasopressin. Hemodynamic monitoring recomme…
- Vasopressin + Ifosfamide— Suspected of causing SIADH; may increase pressor and antidiuretic effects of vasopressin. Hemodynamic monitoring recomme…
- Vasopressin + Indomethacin— May prolong the effect of vasopressin on cardiac index and systemic vascular resistance. Hemodynamic monitoring recommen…
- Vasopressin + Ketamine Hydrochloride— May enhance the sympathomimetic effects of ketamine. Closely monitor vital signs and consider individualized dose adjust…
- Vasopressin + Lithium— Suspected of causing diabetes insipidus; may decrease pressor and antidiuretic effects of vasopressin. Hemodynamic monit…
- Vasopressin + Methyldopa— Suspected of causing SIADH; may increase pressor and antidiuretic effects of vasopressin. Hemodynamic monitoring recomme…
- Vasopressin + Pentamidine— Suspected of causing SIADH; may increase pressor and antidiuretic effects of vasopressin. Hemodynamic monitoring recomme…
- Vasopressin + Sodium Chloride, Calcium Chloride, And Potassium Chloride— Concomitant use may increase risk of hyponatremia. Avoid use; if unavoidable, closely monitor serum sodium concentration…
- Vasopressin + Vincristine— Suspected of causing SIADH; may increase pressor and antidiuretic effects of vasopressin. Hemodynamic monitoring recomme…