Concurrent use may cause increased sedative effects and additive CNS depression with trihexyphenidyl.
Source: NLP:trihexyphenidyl hydrochloride
Trihexyphenidyl Hydrochloride Interactions
Brand names: Trihexyphenidyl Hydrochloride
Route: Oral
Contraindications
CONTRAINDICATIONS Trihexyphenidyl HCl is contraindicated in patients with hypersensitivity to trihexyphenidyl HCl or to any of the tablet ingredients. Trihexyphenidyl HCl is also contraindicated in patients with narrow angle glaucoma. Blindness after long-term use due to narrow angle glaucoma has been reported.
Pregnancy & Breastfeeding
Pregnancy TERATOGENIC EFFECTS PREGNANCY CATEGORY C Animal reproduction studies to evaluate teratogenic and embryotoxic potential have not been conducted with trihexyphenidyl HCl. It is also not known whether trihexyphenidyl HCl can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Trihexyphenidyl HCl should be given to a pregnant woman only if clearly needed.
5 interactions on record
Additive effects with trihexyphenidyl; abuse potential exists with concurrent use.
Source: NLP:trihexyphenidyl hydrochloride
Additive effects with trihexyphenidyl; abuse potential exists with concurrent use.
Source: NLP:trihexyphenidyl hydrochloride
Concomitant administration may increase drug-induced involuntary movements; dose of either drug may need reduction.
Source: NLP:trihexyphenidyl hydrochloride
May intensify anticholinergic effects of trihexyphenidyl due to secondary anticholinergic activities.
Source: NLP:trihexyphenidyl hydrochloride