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Hyoscyamine Sulfate

Also known as: Hyoscyamine Sulfate Tab

Route: Oral

Check Hyoscyamine Sulfate Interactions →

13 interactions on record

Hyoscyamine Sulfate has 13 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Amantadine, Antacids Containing Calcium, Antidiarrheals (Adsorbent). Patients taking Hyoscyamine Sulfate should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 13
Moderate: 13

Moderate (13)

Hyoscyamine Sulfate + Amantadine— Additive adverse effects from cholinergic blockade may occur when combined with hyoscyamine sulfate.
Hyoscyamine Sulfate + Antacids Containing Calcium— Absorption of antacids may be decreased during concurrent use due to decreased gastrointestinal motility and delayed gas…
Hyoscyamine Sulfate + Antidiarrheals (Adsorbent)— Absorption of adsorbent antidiarrheals may be decreased during concurrent use due to decreased gastrointestinal motility…
Hyoscyamine Sulfate + Antihistamines— Some antihistamines may cause additive adverse effects from cholinergic blockade when combined with hyoscyamine sulfate.
Hyoscyamine Sulfate + Cyclopropane— Drug interactions may occur when hyoscyamine sulfate is used with cyclopropane.
Hyoscyamine Sulfate + Haloperidol— Drug interactions may occur when hyoscyamine sulfate is used with haloperidol.
Hyoscyamine Sulfate + Ketoconazole— Absorption of ketoconazole may be decreased during concurrent use due to decreased gastrointestinal motility and delayed…
Hyoscyamine Sulfate + Metoclopramide— Drug interactions may occur when hyoscyamine sulfate is used with metoclopramide.
Hyoscyamine Sulfate + Monoamine Oxidase Inhibitors (Maois)— Additive adverse effects from cholinergic blockade may occur when combined with hyoscyamine sulfate.
Hyoscyamine Sulfate + Opioid Analgesics— Drug interactions may occur when hyoscyamine sulfate is used with opioid analgesics.
Hyoscyamine Sulfate + Other Anticholinergic Agents— Drug interactions may occur when hyoscyamine sulfate is used with other anticholinergics.
Hyoscyamine Sulfate + Phenothiazines— Additive adverse effects from cholinergic blockade may occur when combined with hyoscyamine sulfate.
Hyoscyamine Sulfate + Potassium Chloride— Absorption of potassium chloride may be decreased during concurrent use due to decreased gastrointestinal motility and d…

Hyoscyamine Sulfate + Amantadine🟡Moderate

Additive adverse effects from cholinergic blockade may occur when combined with hyoscyamine sulfate.

Hyoscyamine Sulfate + Antacids Containing Calcium🟡Moderate

Absorption of antacids may be decreased during concurrent use due to decreased gastrointestinal motility and delayed gastric emptying.

Hyoscyamine Sulfate + Antidiarrheals (Adsorbent)🟡Moderate

Absorption of adsorbent antidiarrheals may be decreased during concurrent use due to decreased gastrointestinal motility and delayed gastric emptying.

Hyoscyamine Sulfate + Antihistamines🟡Moderate

Some antihistamines may cause additive adverse effects from cholinergic blockade when combined with hyoscyamine sulfate.

Hyoscyamine Sulfate + Cyclopropane🟡Moderate

Drug interactions may occur when hyoscyamine sulfate is used with cyclopropane.

Hyoscyamine Sulfate + Haloperidol🟡Moderate

Drug interactions may occur when hyoscyamine sulfate is used with haloperidol.

Hyoscyamine Sulfate + Ketoconazole🟡Moderate

Absorption of ketoconazole may be decreased during concurrent use due to decreased gastrointestinal motility and delayed gastric emptying.

Hyoscyamine Sulfate + Metoclopramide🟡Moderate

Drug interactions may occur when hyoscyamine sulfate is used with metoclopramide.

Hyoscyamine Sulfate + Monoamine Oxidase Inhibitors (Maois)🟡Moderate

Additive adverse effects from cholinergic blockade may occur when combined with hyoscyamine sulfate.

Hyoscyamine Sulfate + Opioid Analgesics🟡Moderate

Drug interactions may occur when hyoscyamine sulfate is used with opioid analgesics.

Hyoscyamine Sulfate + Other Anticholinergic Agents🟡Moderate

Drug interactions may occur when hyoscyamine sulfate is used with other anticholinergics.

Hyoscyamine Sulfate + Phenothiazines🟡Moderate

Additive adverse effects from cholinergic blockade may occur when combined with hyoscyamine sulfate.

Hyoscyamine Sulfate + Potassium Chloride🟡Moderate

Absorption of potassium chloride may be decreased during concurrent use due to decreased gastrointestinal motility and delayed gastric emptying.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.