Dextrose Injection can affect glycemic control; monitor blood glucose concentrations, fluid balance, serum electrolyte concentrations and acid-base balance when used with anti-epileptics.
Source: NLP:dextrose monohydrate
Dextrose Monohydrate Interactions
Brand names: Dextrose
Route: Intravenous
Contraindications
4 CONTRAINDICATIONS Dextrose Injection (25%) is contraindicated in patients with: • Intracranial or intraspinal hemorrhage because Dextrose Injection (25%) can worsen cerebral edema by causing a fluid shift across the blood-brain barrier. • Severe dehydration because of the potential to worsen the patient’s hyperosmolar state. • Known hypersensitivity to dextrose [see Warnings and Precautions (5.2) ]. • Intracranial or intraspinal hemorrhage. ( 4 ) • Severe dehydration. ( 4 ) • Hypersensitivity to dextrose. ( 4 )
Pregnancy & Breastfeeding
8.1 Pregnancy Risk Summary Appropriate administration of Dextrose Injection during pregnancy is not expected to cause adverse developmental outcomes, including congenital malformations. Animal reproduction studies have not been conducted with injectable dextrose solutions. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. All pregnancies have a background risk of birth defect, loss, or other adverse outcomes. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2 to 4% and 15 to 20%, respectively.
5 interactions on record
Certain cytotoxic drugs may increase risk of hyponatremia through SIADH. Monitor serum sodium concentrations closely during concomitant use.
Source: NLP:dextrose monohydrate
Dextrose Monohydrate + DiureticsModerate
Dextrose Injection can affect fluid and/or electrolyte balance; monitor blood glucose, fluid balance, serum electrolyte concentrations and acid-base balance when used with diuretics.
Source: NLP:dextrose monohydrate
Concomitant use may increase risk of hyponatremia through SIADH. Avoid use; if unavoidable, closely monitor serum sodium concentrations.
Source: NLP:dextrose monohydrate
Concomitant use may increase risk of hyponatremia. Avoid use; if unavoidable, closely monitor serum sodium concentrations.
Source: NLP:dextrose monohydrate