Mirabegron has 7 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Digoxin, Ketoconazole, Oral Contraceptives. Patients taking Mirabegron should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 7
- Major
- 1
- Moderate
- 6
Major (1)
- Mirabegron + Digoxin— Mirabegron increases digoxin Cmax by 29% and AUC by 27%. Use lowest digoxin dose and monitor serum concentrations for do…
Moderate (6)
- Mirabegron + Ketoconazole— Drug interaction study conducted; no dose adjustment recommended when coadministered with mirabegron.
- Mirabegron + Oral Contraceptives— Drug interaction study conducted; no dose adjustment recommended when coadministered with mirabegron.
- Mirabegron + Rifampin— Drug interaction study conducted; no dose adjustment recommended when coadministered with mirabegron.
- Mirabegron + Solifenacin Succinate— Drug interaction study conducted; no dose adjustment recommended when coadministered with mirabegron.
- Mirabegron + Tamsulosin— Drug interaction study conducted; no dose adjustment recommended when coadministered with mirabegron.
- Mirabegron + Warfarin— Mirabegron increases warfarin Cmax (~4%) and AUC (~9%). Effect on multiple-dose warfarin pharmacodynamics (INR, prothrom…