Concomitant administration of hydrochlorothiazide alone with topiramate alone has been shown to increase the C max and AUC of topiramate by 27% and 29%, respectively.
Source: FDA drug label - phentermine and topiramate
Phentermine And Topiramate Interactions
Brand names: Qsymia
Cytochrome P450 3A4 Inducers · Cytochrome P450 2C19 Inhibitors
1 interaction on record