Brimonidine has 8 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Alcohol, Anti-Arrhythmics, Barbiturates. Patients taking Brimonidine should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 8
- Moderate
- 8
Moderate (8)
- Brimonidine + Alcohol— Possibility of additive or potentiating CNS depressant effect with brimonidine.
- Brimonidine + Anti-Arrhythmics— Alpha-2 agonists may reduce blood pressure; caution advised when using anti-hypertensives concurrently.
- Brimonidine + Barbiturates— Possibility of additive or potentiating CNS depressant effect with brimonidine.
- Brimonidine + Cardiac Glycosides— Alpha-2 agonists may reduce blood pressure; caution advised when using cardiac glycosides concurrently.
- Brimonidine + Monoamine Oxidase Inhibitors (Maois)— MAO inhibitors may interfere with brimonidine metabolism, potentially resulting in increased systemic side effects such …
- Brimonidine + Nonselective Beta-Adrenergic Antagonists— Alpha-2 agonists may reduce blood pressure; caution advised when using beta-blockers concurrently.
- Brimonidine + Sedatives— Possibility of additive or potentiating CNS depressant effect with brimonidine.
- Brimonidine + Topical Local Anesthetics— Possibility of additive or potentiating CNS depressant effect with brimonidine.