Donepezil has 1 known drug interaction based on U.S. FDA drug labeling data. Notable interactions include combinations with Ramelteon. Patients taking Donepezil should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 1
- Moderate
- 1
Moderate (1)
- Donepezil + Ramelteon— Increases ramelteon AUC by approximately 100% and Cmax by 87%; patients should be closely monitored.