Glycerol Phenylbutyrate has 8 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Alfentanil, Corticosteroids, Cyclosporine. Patients taking Glycerol Phenylbutyrate should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 8
- Moderate
- 8
Moderate (8)
- Glycerol Phenylbutyrate + Alfentanil— Glycerol phenylbutyrate may decrease systemic exposure. Monitor for decreased efficacy of this narrow therapeutic index …
- Glycerol Phenylbutyrate + Corticosteroids— May increase plasma ammonia levels through protein breakdown. Monitor ammonia levels closely during concomitant use.
- Glycerol Phenylbutyrate + Cyclosporine— Glycerol phenylbutyrate may decrease systemic exposure. Monitor for decreased efficacy of this narrow therapeutic index …
- Glycerol Phenylbutyrate + Haloperidol— May induce hyperammonemia. Monitor ammonia levels closely when used concomitantly in patients with UCDs.
- Glycerol Phenylbutyrate + Midazolam— ( 7.3 ) Midazolam : Decreased exposure; monitor for suboptimal effect of midazolam. Midazolam Concomitant use of glycero…
- Glycerol Phenylbutyrate + Probenecid— May inhibit renal excretion of glycerol phenylbutyrate metabolites including PAGN and PAA.
- Glycerol Phenylbutyrate + Quinidine— Glycerol phenylbutyrate may decrease systemic exposure. Monitor for decreased efficacy of this narrow therapeutic index …
- Glycerol Phenylbutyrate + Valproic Acid— May induce hyperammonemia. Monitor ammonia levels closely when used concomitantly in patients with UCDs.