Additive CNS depression may occur when antihistamines are administered concomitantly with alcohol.
Source: NLP:clemastine fumarate
Brand names: Clemastine Fumarate
Route: Oral
Contraindications
CONTRAINDICATIONS Antihistamines are contraindicated in patients hypersensitive to the drug or to other antihistamines of similar chemical structure (see PRECAUTIONS- Drug Interactions ). Antihistamines should not be used in newborn or premature infants . Because of the higher risk of antihistamines for infants generally and for newborns and prematures in particular, antihistamine therapy is contraindicated in nursing mothers (see PRECAUTIONS-Nursing Mothers ).
Pregnancy & Breastfeeding
Pregnancy Teratogenic Effects Pregnancy Category B Oral reproduction studies performed with clemastine fumarate in rats and rabbits at doses up to 312 and 188 times the adult human doses respectively, have revealed no evidence of teratogenic effects. There are no adequate and well-controlled studies of clemastine fumarate in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used in pregnancy only if clearly needed.
5 interactions on record
Additive CNS depression may occur when antihistamines are administered concomitantly with alcohol.
Source: NLP:clemastine fumarate
Additive CNS depression may occur when antihistamines are administered concomitantly with barbiturates.
Source: NLP:clemastine fumarate
MAO inhibitors prolong and intensify the anticholinergic (drying) effects of clemastine fumarate.
Source: NLP:clemastine fumarate
MAO inhibitors prolong and intensify the anticholinergic effects of antihistamines.
Source: NLP:clemastine fumarate
Additive CNS depression may occur when antihistamines are administered concomitantly with tranquilizers.
Source: NLP:clemastine fumarate