Ioflupane I-123 + AmoxapineModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 Interactions
Brand names: Datscan
Radioactive Diagnostic Agent · Radiopharmaceutical Activity
Route: Intravenous
Contraindications
4 CONTRAINDICATIONS DATSCAN is contraindicated in patients with known serious hypersensitivity to ioflupane I 123 [see Warnings and Precautions (5.1) ] . Known serious hypersensitivity to ioflupane I 123 ( 4 )
Pregnancy & Breastfeeding
8.1 Pregnancy Risk Summary Radioactive iodine products cross the placenta and can permanently impair fetal thyroid function. Administration of an appropriate thyroid blocking agent is recommended before use of DATSCAN in a pregnant woman to protect the woman and fetus from accumulation of iodine-123 [see Dosage and Administration (2.3) ] . There are no available data on DATSCAN use in pregnant women to evaluate for a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes. Animal reproduction studies have not been conducted with ioflupane I 123. All radiopharmaceuticals have the potential to cause fetal harm depending on the fetal stage of development and the magnitude of the radiation dose. Administration of DATSCAN at a dose of 185 MBq (5 mCi) results in an absorbed radiation dose to the uterus of 0.3 rad (3.0 mGy). Radiation doses greater than 15 rad (150 mGy) have been associated with congenital anomalies but doses under 5 rad (50 mGy) generally have not. Advise pregnant women of the potential risks of fetal exposure to radiation doses with administration of DATSCAN. The estimated background risk of major birth defects and miscarriage for the indicated population(s) is unknown. All pregnancies have a background risk of birth defect, loss, or other adverse outcomes. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively.
17 interactions on record
Ioflupane I-123 + AmphetamineModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + ArmodafinilModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + BenztropineModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + BupropionModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + BuspironeModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + CitalopramModerate
May increase or decrease ioflupane binding to dopamine transporter and may interfere with imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + CocaineModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + MazindolModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + ModafinilModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + ParoxetineModerate
May increase or decrease ioflupane binding to dopamine transporter and may interfere with imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + PhentermineModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + SelegilineModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123
Ioflupane I-123 + SertralineModerate
Binds to dopamine transporter with high affinity and may interfere with Ioflupane I-123 imaging results.
Source: NLP:ioflupane i-123