Anti-Arrhythmics has 19 known drug interactions based on U.S. FDA drug labeling data. Of these, 2 are contraindicated combinations that should be avoided entirely. 8 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Nilotinib, Tretinoin, Albuterol Sulfate. Patients taking Anti-Arrhythmics should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 19
- Contraindicated
- 2
- Major
- 8
- Moderate
- 8
Contraindicated (2)
- Anti-Arrhythmics + Nilotinib— Avoid coadministration. Nilotinib is associated with clinically significant concentration-dependent QT prolongation; age…
- Anti-Arrhythmics + Tretinoin— Fatal thrombotic complications reported with concomitant use. Avoid concomitant use.
Major (8)
- Anti-Arrhythmics + Albuterol Sulfate— Patients receiving epinephrine with anti-arrhythmics should be observed carefully for development of cardiac arrhythmias…
- Anti-Arrhythmics + Auvi-Q— Increased risk of cardiac arrhythmias when used with epinephrine; careful observation required.
- Anti-Arrhythmics + Epinephrine— Patients receiving epinephrine with anti-arrhythmics should be observed carefully for development of cardiac arrhythmias…
- Anti-Arrhythmics + Epinephrine 0.15 Pediatrics— Patients receiving epinephrine with anti-arrhythmics should be observed carefully for development of cardiac arrhythmias…
- Anti-Arrhythmics + Epinephrine 0.3 Adults— Patients receiving epinephrine with anti-arrhythmics should be observed carefully for development of cardiac arrhythmias…
- Anti-Arrhythmics + Glycopyrrolate— Potential for additive anticholinergic interaction resulting in increased anticholinergic adverse reactions.
- Anti-Arrhythmics + Lidocaine Hydrochloride— Concurrent use with lidocaine solutions containing epinephrine or norepinephrine may produce severe, prolonged hypertens…
- Anti-Arrhythmics + Pyridostigmine Bromide— Should be used cautiously or avoided during pyridostigmine treatment due to interference with neuromuscular transmission…
Moderate (8)
- Anti-Arrhythmics + Brimonidine— Alpha-2 agonists may reduce blood pressure; caution advised when using anti-hypertensives concurrently.
- Anti-Arrhythmics + Brimonidine Tartrate— Alpha-2 agonists may reduce blood pressure; caution advised when used with anti-hypertensives due to potential additive …
- Anti-Arrhythmics + Clonidine Hydrochloride— Tricyclic anti-depressants may antagonize the hypotensive effects of clonidine.
- Anti-Arrhythmics + Dextrose Monohydrate— Dextrose Injection can affect glycemic control; monitor blood glucose concentrations, fluid balance, serum electrolyte c…
- Anti-Arrhythmics + Oxymetazoline Hydrochloride— Alpha-adrenergic agonists may impact blood pressure; caution advised when used with anti-hypertensive drugs.
- Anti-Arrhythmics + Oxymetazoline Hydrochloride Ophthalmic— Alpha-adrenergic agonists may impact blood pressure; caution advised when using anti-hypertensives concurrently.
- Anti-Arrhythmics + Sildenafil— Sildenafil can potentiate the hypotensive effects of anti-hypertensive agents.
- Anti-Arrhythmics + Thalidomide— Anti-anxiety agents concomitantly with thalidomide may cause additive sedative effect and should be avoided.