Concurrent administration of vasopressor drugs and ergot-type oxytocic drugs may cause severe, persistent hypertension or cerebrovascular accidents.
Source: NLP:sodium hyaluronate, lidocaine, isopropyl alcohol
Brand names: Hyronan
Route: Epidural, Infiltration, Intra-Articular, Topical
Contraindications
CONTRAINDICATIONS Lidocaine hydrochloride is contraindicated in patients with a known history of hypersensitivity to local anesthetics of the amide type.
Pregnancy & Breastfeeding
Pregnancy Teratogenic Effects Reproduction studies have been performed in rats at doses up to 6.6 times the human dose and have revealed no evidence of harm to the fetus caused by lidocaine hydrochloride. There are, however, no adequate and well-controlled studies in pregnant women. Animal reproduction studies are not always predictive of human response. General consideration should be given to this fact before administering lidocaine hydrochloride to women of childbearing potential, especially during early pregnancy when maximum organogenesis takes place.
4 interactions on record
Concurrent administration of vasopressor drugs and ergot-type oxytocic drugs may cause severe, persistent hypertension or cerebrovascular accidents.
Source: NLP:sodium hyaluronate, lidocaine, isopropyl alcohol
Administration of local anesthetic solutions containing epinephrine or norepinephrine to patients receiving MAOIs may produce severe, prolonged hypertension.
Source: NLP:sodium hyaluronate, lidocaine, isopropyl alcohol
Butyrophenones may reduce or reverse the pressor effect of epinephrine. Concurrent use should generally be avoided; careful patient monitoring is essential if necessary.
Source: NLP:sodium hyaluronate, lidocaine, isopropyl alcohol
Phenothiazines may reduce or reverse the pressor effect of epinephrine. Concurrent use should generally be avoided; careful patient monitoring is essential if necessary.
Source: NLP:sodium hyaluronate, lidocaine, isopropyl alcohol