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Atazanavir And Cobicistat

Also known as: Evotaz

Cytochrome P450 3A InhibitorCytochrome P450 3A InhibitorsP-Glycoprotein Inhibitors

Route: Oral

Check Atazanavir And Cobicistat Interactions →
54 interactions on record

Atazanavir And Cobicistat has 54 known drug interactions based on U.S. FDA drug labeling data. Of these, 14 are contraindicated combinations that should be avoided entirely. 3 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Alfuzosin, Apalutamide, Efavirenz, Emtricitabine And Tenofovir Disoproxil Fumarate. Patients taking Atazanavir And Cobicistat should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total
54
Contraindicated
14
Major
3
Moderate
1

Contraindicated (14)

Major (3)

Moderate (1)

Atazanavir And Cobicistat + Midazolam⛔Contraindicated

Sedatives/Hypnotics: Benzodiazepines midazolam (oral) triazolam ↑ midazolam ↑ triazolam Coadministration of triazolam or orally administered midazolam is contraindicated due to the potential for serious and/or life-threatening events such as prolonged or increased sedation or respiratory depression. Triazolam and orally administered midazolam are extensively metabolized by CYP3A4 [see Contraindications (4) ] . Other Benzodiazepines : clorazepate diazepam estazolam flurazepam parenterally administered midazolam ↑ sedatives/hypnotics Parenterally administered midazolam: Coadministration should be done in a setting which ensures close clinical monitoring and appropriate medical management in case of respiratory depression and/or prolonged sedation.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.