Does Atazanavir And Cobicistat Interact with Fostamatinib?
Atazanavir And Cobicistat and Fostamatinib have a unknown drug interaction according to U.S. FDA drug labeling data. Kinase inhibitors: fostamatinib ↑ R406 active metabolite of fostamatinib Coadministration with fostamatinib may increase the plasma concentration of R406, the active metabolite of fostamatinib. Fostamatinib dose reduction may be required. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Atazanavir And Cobicistat Class
- Cytochrome P450 3A Inhibitor
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Atazanavir And Cobicistat and your doctor is considering prescribing Fostamatinib (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider