Drugs That Prolong The Qt Interval has 14 known drug interactions based on U.S. FDA drug labeling data. Of these, 2 are contraindicated combinations that should be avoided entirely. 7 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Phenobarbital Sodium, Ziprasidone Mesylate, Arformoterol Tartrate. Patients taking Drugs That Prolong The Qt Interval should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 14
- Contraindicated
- 2
- Major
- 7
- Moderate
- 5
Contraindicated (2)
- Drugs That Prolong The Qt Interval + Phenobarbital Sodium— Avoid concomitant use with phenobarbital.
- Drugs That Prolong The Qt Interval + Ziprasidone Mesylate— Ziprasidone should not be used in combination with other drugs that have demonstrated QT prolongation due to risk of ser…
Major (7)
- Drugs That Prolong The Qt Interval + Arformoterol Tartrate— QTc prolonging drugs may potentiate cardiovascular effects of arformoterol. Use with extreme caution.
- Drugs That Prolong The Qt Interval + Droperidol— Potential pharmacodynamic interaction with QT-prolonging neuroleptics; may precipitate arrhythmias.
- Drugs That Prolong The Qt Interval + Givinostat— Avoid concomitant use with QTc-prolonging drugs. Givinostat causes QTc prolongation; combined use may result in greater …
- Drugs That Prolong The Qt Interval + Haloperidol Decanoate— Concomitant use may result in greater QTc interval prolongation and serious adverse reactions including torsade de point…
- Drugs That Prolong The Qt Interval + Inotuzumab Ozogamicin— Concomitant use may increase risk of clinically significant QTc interval prolongation and Torsades de Pointes. Discontin…
- Drugs That Prolong The Qt Interval + Oxaliplatin— QT interval prolongation and ventricular arrhythmias can occur with coadministration. Avoid coadministration of oxalipla…
- Drugs That Prolong The Qt Interval + Ziftomenib— Avoid concomitant use. If unavoidable, obtain ECGs and monitor for QTc prolongation. Ziftomenib causes QTc prolongation;…
Moderate (5)
- Drugs That Prolong The Qt Interval + Mannitol— Electrolyte imbalances from mannitol may result in cardiac adverse reactions; monitor serum electrolytes.
- Drugs That Prolong The Qt Interval + Nipocalimab— Concomitant use may lower systemic exposures and reduce effectiveness. Closely monitor for reduced effectiveness; consid…
- Drugs That Prolong The Qt Interval + Olanzapine And Fuoxetine— Use olanzapine and fluoxetine capsules with caution in combination with other QT-prolonging drugs.
- Drugs That Prolong The Qt Interval + Primaquine Phosphate— Caution is advised when primaquine is used concomitantly with other drugs that prolong the QT interval due to potential …
- Drugs That Prolong The Qt Interval + Rozanolixizumab— Concomitant use may lower systemic exposures and reduce effectiveness. Closely monitor for reduced effectiveness.