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Brivaracetam Injection

Also known as: Brivaracetam

Epoxide Hydrolase Inhibitors

Route: Intravenous

Check Brivaracetam Injection Interactions →

4 interactions on record

Brivaracetam Injection has 4 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Carbamazepine, Phenytoin, Rifampin. Patients taking Brivaracetam Injection should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 4
Moderate: 3
Minor: 1

Moderate (3)

Brivaracetam Injection + Carbamazepine— Brivaracetam may increase exposure to carbamazepine-epoxide (active metabolite); carbamazepine dose reduction should be …
Brivaracetam Injection + Phenytoin— Brivaracetam can increase plasma concentrations of phenytoin; phenytoin levels should be monitored when brivaracetam is …
Brivaracetam Injection + Rifampin— Rifampin decreases brivaracetam plasma concentrations through CYP2C19 induction, requiring up to 100% dosage increase of…

Minor (1)

Brivaracetam Injection + Levetiracetam— Brivaracetam provided no added therapeutic benefit when co-administered with levetiracetam.

Brivaracetam Injection + Carbamazepine🟡Moderate

Brivaracetam may increase exposure to carbamazepine-epoxide (active metabolite); carbamazepine dose reduction should be considered if tolerability issues arise.

Brivaracetam Injection + Phenytoin🟡Moderate

Brivaracetam can increase plasma concentrations of phenytoin; phenytoin levels should be monitored when brivaracetam is added or discontinued.

Brivaracetam Injection + Rifampin🟡Moderate

Rifampin decreases brivaracetam plasma concentrations through CYP2C19 induction, requiring up to 100% dosage increase of brivaracetam.

Brivaracetam Injection + Levetiracetam🟢Minor

Brivaracetam provided no added therapeutic benefit when co-administered with levetiracetam.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.