Carospir has 12 known drug interactions based on U.S. FDA drug labeling data. 9 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Angiotensin Ii, Cholestyramine Light, Digoxin. Patients taking Carospir should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 12
- Major
- 9
- Moderate
- 1
Major (9)
- Carospir + Angiotensin Ii— Concomitant administration can lead to severe hyperkalemia. Check serum potassium levels when ARB therapy is altered.
- Carospir + Cholestyramine Light— Hyperkalemic metabolic acidosis has been reported with concomitant use of CAROSPIR and cholestyramine.
- Carospir + Digoxin— CAROSPIR increases apparent exposure to digoxin. Reduce digoxin dose by 15-30% and monitor serum digoxin concentrations.
- Carospir + Heparin— Heparin may increase serum potassium, leading to severe hyperkalemia when used with CAROSPIR.
- Carospir + Lithium— CAROSPIR reduces renal clearance of lithium, increasing risk of lithium toxicity. Monitor lithium levels periodically.
- Carospir + Low Molecular Weight Heparin— Low molecular weight heparin may increase serum potassium, leading to severe hyperkalemia when used with CAROSPIR.
- Carospir + Mao Inhibitors— Concomitant administration can lead to severe hyperkalemia. Check serum potassium levels when ACE inhibitor therapy is a…
- Carospir + Potassium Supplements— Concomitant administration with potassium supplementation can lead to severe hyperkalemia. Discontinue in heart failure …
- Carospir + Trimethoprim— Trimethoprim may increase serum potassium, leading to severe hyperkalemia when used with CAROSPIR.
Moderate (1)
- Carospir + Aspirin— Acetylsalicylic acid may reduce efficacy of CAROSPIR. May require higher maintenance dose; monitor patient closely.