H2 Blockers has 3 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Cefpodoxime Proxetil, Folic Acid, Risedronate Sodium. Patients taking H2 Blockers should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 3
Moderate: 3

Moderate (3)

H2 Blockers + Cefpodoxime Proxetil— Reduce peak plasma levels by 24-42% and extent of absorption by 27-32%, but do not alter absorption rate.
H2 Blockers + Folic Acid— H2 blockers impair gastrointestinal folate uptake through pH elevation and transporter inhibition.
H2 Blockers + Risedronate Sodium— H2 blockers may cause faster drug release and are not recommended for concomitant use with risedronate sodium.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.