Direct Renin Inhibitors has 2 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Lisinopril And Hydrochlorothiazide Tablets, Amifampridine Phosphate. Patients taking Direct Renin Inhibitors should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 2
- Major
- 1
- Moderate
- 1
Major (1)
- Direct Renin Inhibitors + Lisinopril And Hydrochlorothiazide Tablets— Direct renin inhibitors combined with lisinopril are associated with increased risk of hypotension, syncope, hyperkalemi…
Moderate (1)
- Direct Renin Inhibitors + Amifampridine Phosphate— Concomitant use may increase cholinergic effects and increase risk of adverse reactions.