Sevelamer has 4 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Mycophenilic Acid, Levothyroxine Sodium, Liothyronine Sodium. Patients taking Sevelamer should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 4
- Major
- 1
- Moderate
- 3
Major (1)
- Sevelamer + Mycophenilic Acid— May decrease mycophenolic acid plasma concentrations; concomitant use is not recommended.
Moderate (3)
- Sevelamer + Levothyroxine Sodium— Ion exchange resin known to decrease levothyroxine absorption, potentially resulting in hypothyroidism.
- Sevelamer + Liothyronine Sodium— Ion exchange resin known to decrease thyroid hormone absorption, potentially resulting in hypothyroidism. Administer lio…
- Sevelamer + Mycophenolate Mofetil— Calcium-free phosphate binder that decreases MPA systemic exposure, which may reduce MYHIBBIN efficacy. Administer at le…