Haloperidol Lactate has 29 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Alcohol, Alprazolam, Amiodarone. Patients taking Haloperidol Lactate should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 29
- Moderate
- 29
Moderate (29)
- Haloperidol Lactate + Alcohol— CNS depressant that haloperidol may potentiate, increasing risk of enhanced CNS depression.
- Haloperidol Lactate + Alprazolam— CYP3A4 inhibitor that increases haloperidol plasma concentrations, raising risk of adverse events including QTc prolonga…
- Haloperidol Lactate + Amiodarone— Class 3 antiarrhythmic that prolongs QTc interval; caution advised when used with haloperidol due to risk of QT prolonga…
- Haloperidol Lactate + Buspirone— Increases haloperidol plasma concentrations, raising risk of adverse events including QTc interval prolongation.
- Haloperidol Lactate + Chlorpromazine— CYP2D6 inhibitor that increases haloperidol plasma concentrations, raising risk of adverse events including QTc prolonga…
- Haloperidol Lactate + Citalopram— Drug known to prolong QTc interval; caution advised when used with haloperidol due to risk of QT prolongation.
- Haloperidol Lactate + Corticosteroids— Drugs that cause electrolyte imbalance; caution advised due to risk of hypokalemia and hypomagnesemia which increase QT …
- Haloperidol Lactate + Disopyramide— Class 1A antiarrhythmic that prolongs QTc interval; caution advised when used with haloperidol due to risk of QT prolong…
- Haloperidol Lactate + Diuretics— Drugs that cause electrolyte imbalance; caution advised due to risk of hypokalemia and hypomagnesemia which increase QT …
- Haloperidol Lactate + Dopamine Agonists— Haloperidol may impair antiparkinson effects of dopamine agonists; extrapyramidal symptoms may occur if both are discont…
- Haloperidol Lactate + Erythromycin— Drug known to prolong QTc interval; caution advised when used with haloperidol due to risk of QT prolongation.
- Haloperidol Lactate + Fluoxetine— Combined CYP3A4 and CYP2D6 inhibitor that increases haloperidol plasma concentrations, raising risk of adverse events in…
- Haloperidol Lactate + Fluvoxamine— Combined CYP3A4 and CYP2D6 inhibitor that increases haloperidol plasma concentrations, raising risk of adverse events in…
- Haloperidol Lactate + Itraconazole— CYP3A4 inhibitor that increases haloperidol plasma concentrations, raising risk of adverse events including QTc prolonga…
- Haloperidol Lactate + Ketoconazole— CYP3A4 inhibitor that increases haloperidol plasma concentrations; QTc prolongation observed when combined with paroxeti…
- Haloperidol Lactate + Levodopa— Haloperidol may impair antiparkinson effects of levodopa; extrapyramidal symptoms may occur if both discontinued simulta…
- Haloperidol Lactate + Levofloxacin— Drug known to prolong QTc interval; caution advised when used with haloperidol due to risk of QT prolongation.
- Haloperidol Lactate + Methadone— Drug known to prolong QTc interval; caution advised when used with haloperidol due to risk of QT prolongation.
- Haloperidol Lactate + Nefazodone— CYP3A4 inhibitor that increases haloperidol plasma concentrations, raising risk of adverse events including QTc prolonga…
- Haloperidol Lactate + Paroxetine— CYP2D6 inhibitor that increases haloperidol plasma concentrations; QTc prolongation observed when combined with ketocona…
- Haloperidol Lactate + Procainamide— Class 1A antiarrhythmic that prolongs QTc interval; caution advised when used with haloperidol due to risk of QT prolong…
- Haloperidol Lactate + Promethazine— CYP2D6 inhibitor that increases haloperidol plasma concentrations, raising risk of adverse events including QTc prolonga…
- Haloperidol Lactate + Quinidine— Class 1A antiarrhythmic that prolongs QTc interval and inhibits CYP2D6; caution advised due to risk of QT prolongation a…
- Haloperidol Lactate + Ritonavir— CYP3A4 and CYP2D6 inhibitor that increases haloperidol plasma concentrations, raising risk of adverse events including Q…
- Haloperidol Lactate + Sertraline— CYP2D6 inhibitor that increases haloperidol plasma concentrations, raising risk of adverse events including QTc prolonga…
- Haloperidol Lactate + Sotalol— Class 3 antiarrhythmic that prolongs QTc interval; caution advised when used with haloperidol due to risk of QT prolonga…
- Haloperidol Lactate + Topical Local Anesthetics— CNS depressants; haloperidol may potentiate their effects and enhance CNS depression.
- Haloperidol Lactate + Venlafaxine— CYP2D6 inhibitor that increases haloperidol plasma concentrations, raising risk of adverse events including QTc prolonga…
- Haloperidol Lactate + Ziprasidone— Drug known to prolong QTc interval; caution advised when used with haloperidol due to risk of QT prolongation.