Dexmedetomidine Hydrochloride has 6 known drug interactions based on U.S. FDA drug labeling data. 5 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Alfentanil, Isoflurane, Midazolam. Patients taking Dexmedetomidine Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 6
- Major
- 5
- Minor
- 1
Major (5)
- Dexmedetomidine Hydrochloride + Alfentanil— Enhancement of pharmacodynamic effects. Reduction in dosage of dexmedetomidine or alfentanil may be required. No pharmac…
- Dexmedetomidine Hydrochloride + Isoflurane— Enhancement of pharmacodynamic effects. Reduction in dosage of dexmedetomidine or isoflurane may be required. No pharmac…
- Dexmedetomidine Hydrochloride + Midazolam— Enhancement of pharmacodynamic effects. Reduction in dosage of dexmedetomidine or midazolam may be required. No pharmaco…
- Dexmedetomidine Hydrochloride + Propofol— Enhancement of pharmacodynamic effects. Reduction in dosage of dexmedetomidine or propofol may be required. No pharmacok…
- Dexmedetomidine Hydrochloride + Sevoflurane— Enhancement of pharmacodynamic effects. Reduction in dosage of dexmedetomidine or sevoflurane may be required.
Minor (1)
- Dexmedetomidine Hydrochloride + Rocuronium— Administration of dexmedetomidine hydrochloride at plasma concentration of 1 ng/mL resulted in no clinically meaningful …