Olodaterol Respimat Inhalation Spray has 8 known drug interactions based on U.S. FDA drug labeling data. 3 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Drugs That Prolong Qtc Interval, Monoamine Oxidase Inhibitors (Maois), Nonselective Beta-Adrenergic Antagonists. Patients taking Olodaterol Respimat Inhalation Spray should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 8
- Major
- 3
- Moderate
- 5
Major (3)
- Olodaterol Respimat Inhalation Spray + Drugs That Prolong Qtc Interval— May potentiate cardiovascular effects of olodaterol and increase risk of ventricular arrhythmias. Use with extreme cauti…
- Olodaterol Respimat Inhalation Spray + Monoamine Oxidase Inhibitors (Maois)— May potentiate action of olodaterol on cardiovascular system. Administer with extreme caution.
- Olodaterol Respimat Inhalation Spray + Nonselective Beta-Adrenergic Antagonists— May decrease effectiveness of olodaterol and produce severe bronchospasm in COPD patients. Use only when medically neces…
Moderate (5)
- Olodaterol Respimat Inhalation Spray + Diuretics— May potentiate hypokalemic effect of olodaterol. Use with caution.
- Olodaterol Respimat Inhalation Spray + Ketoconazole— Strong dual CYP and P-gp inhibitor increases maximum plasma concentrations and AUC of olodaterol 1.7-fold.
- Olodaterol Respimat Inhalation Spray + Potassium Supplements— ECG changes and hypokalemia from these diuretics can be worsened by olodaterol, especially at high doses. Use with cauti…
- Olodaterol Respimat Inhalation Spray + Topical Steroids— May potentiate hypokalemic effect of olodaterol. Use with caution.
- Olodaterol Respimat Inhalation Spray + Xanthine Derivatives— May potentiate hypokalemic effect of olodaterol. Use with caution.