Thyroid hormones increase catabolism of vitamin K-dependent clotting factors, impairing compensatory increases in clotting factor synthesis. Patients may require reduction in anticoagulant dosage.
Source: NLP:thyroid, porcine
Thyroid, Porcine Interactions
Brand names: Niva Thyroid
Route: Oral
FDA Black Box Warning
Drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
Contraindications
CONTRAINDICATIONS Thyroid hormone preparations are generally contraindicated in patients with diagnosed but as yet uncorrected adrenal cortical insufficiency, untreated thyrotoxicosis, and apparent hypersensitivity to any of their active or extraneous constituents. There is no well-documented evidence from the literature, however, of true allergic or idiosyncratic reactions to thyroid hormone.
6 interactions on record
Binds levothyroxine (T4) and liothyronine (T3) in the intestine, impairing absorption of thyroid hormones. Separate administration by 4-5 hours.
Source: NLP:thyroid, porcine
Thyroid, Porcine + ColestipolModerate
Binds levothyroxine (T4) and liothyronine (T3) in the intestine, impairing absorption of thyroid hormones. Separate administration by 4-5 hours.
Source: NLP:thyroid, porcine
Thyroid, Porcine + EstrogensModerate
Increases serum thyroxine-binding globulin (TBg), decreasing free levothyroxine (T4) in patients without functioning thyroid glands. May require increased thyroid dose.
Source: NLP:thyroid, porcine
Thyroid, Porcine + Insulin HumanModerate
Initiating thyroid replacement therapy may increase insulin requirements. Patients should be closely monitored during initiation of thyroid replacement therapy.
Source: NLP:thyroid, porcine
Estrogen-containing formulations increase serum thyroxine-binding globulin (TBg), decreasing free levothyroxine (T4) in patients without functioning thyroid glands. May require increased thyroid dose.
Source: NLP:thyroid, porcine