Ibandronate Sodium has 8 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Acetylsalicylic Acid, Antacids Containing Calcium, Calcium Antagonists. Patients taking Ibandronate Sodium should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 8
- Moderate
- 4
- Minor
- 4
Moderate (4)
- Ibandronate Sodium + Acetylsalicylic Acid— Caution should be exercised with concomitant use of aspirin and ibandronate as both are associated with gastrointestinal…
- Ibandronate Sodium + Antacids Containing Calcium— Antacids interfere with absorption of ibandronate. Patients should take ibandronate at least 60 minutes before antacids.
- Ibandronate Sodium + Calcium Antagonists— Calcium supplements interfere with absorption of ibandronate. Patients should take ibandronate at least 60 minutes befor…
- Ibandronate Sodium + Nonsteroidal Anti-Inflammatory Drugs (Nsaids)— Caution should be exercised with concomitant use of NSAIDs and ibandronate as both are associated with gastrointestinal …
Minor (4)
- Ibandronate Sodium + Melphalan— No interaction observed between intravenous ibandronate (6 mg) and intravenous melphalan (10 mg/m²).
- Ibandronate Sodium + Prednisolone— No interaction observed between intravenous ibandronate (6 mg) and oral prednisolone (60 mg/m²).
- Ibandronate Sodium + Ranitidine— Co-administration with ranitidine resulted in 20% increased bioavailability of ibandronate, which was not considered cli…
- Ibandronate Sodium + Tamoxifen— No interaction observed between oral tamoxifen (30 mg) and intravenous ibandronate (2 mg).