Ferrous Sulfate

4 interactions on record

Ferrous Sulfate has 4 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Cefdinir, Levothyroxine Sodium, Methyldopa. Patients taking Ferrous Sulfate should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 4
Moderate: 4

Moderate (4)

Ferrous Sulfate + Cefdinir— Therapeutic iron supplements containing 60 mg elemental iron reduce cefdinir absorption by 80%. Take cefdinir at least 2…
Ferrous Sulfate + Levothyroxine Sodium— Likely forms a ferric-thyroxine complex that reduces levothyroxine absorption, potentially resulting in hypothyroidism.
Ferrous Sulfate + Methyldopa— Decreases bioavailability of methyldopa and may adversely affect blood pressure control. Coadministration not recommende…
Ferrous Sulfate + Vadadustat— Co-administration decreases vadadustat exposure, which may reduce effectiveness. Stagger administration by at least 1 ho…

Ferrous Sulfate + Cefdinir🟡Moderate

Therapeutic iron supplements containing 60 mg elemental iron reduce cefdinir absorption by 80%. Take cefdinir at least 2 hours before or after iron supplement.

Ferrous Sulfate + Levothyroxine Sodium🟡Moderate

Likely forms a ferric-thyroxine complex that reduces levothyroxine absorption, potentially resulting in hypothyroidism.

Ferrous Sulfate + Methyldopa🟡Moderate

Decreases bioavailability of methyldopa and may adversely affect blood pressure control. Coadministration not recommended.

Ferrous Sulfate + Vadadustat🟡Moderate

Co-administration decreases vadadustat exposure, which may reduce effectiveness. Stagger administration by at least 1 hour.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.