Maribavir has 11 known drug interactions based on U.S. FDA drug labeling data. 4 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Carbamazepine, Ganciclovir, Phenytoin. Patients taking Maribavir should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 11
- Major
- 4
- Moderate
- 3
Major (4)
- Maribavir + Carbamazepine— Strong CYP3A4 inducer that decreases maribavir concentrations. A dose adjustment of LIVTENCITY to 800 mg twice daily is …
- Maribavir + Ganciclovir— LIVTENCITY may antagonize the antiviral activity of ganciclovir by inhibiting human CMV pUL97 kinase, which is required …
- Maribavir + Phenytoin— Strong CYP3A4 inducer that decreases maribavir concentrations. Dose adjustment is recommended when coadministered.
- Maribavir + Valganciclovir— LIVTENCITY may antagonize the antiviral activity of valganciclovir by inhibiting human CMV pUL97 kinase, which is requir…
Moderate (3)
- Maribavir + Digoxin— P-gp substrate with increased concentration when coadministered with LIVTENCITY. Monitor serum digoxin concentrations an…
- Maribavir + Phenobarbital— Moderate CYP3A4 inducer that decreases maribavir concentrations. A dose adjustment of LIVTENCITY is recommended when coa…
- Maribavir + Rifabutin— Moderate CYP3A4 inducer that decreases maribavir concentrations. A dose adjustment of LIVTENCITY is recommended when coa…