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Prilocaine Hcl And Epinephrine

Also known as: Citanest Forte Dental

Route: Submucosal

Check Prilocaine Hcl And Epinephrine Interactions →

33 interactions on record

Prilocaine Hcl And Epinephrine has 33 known drug interactions based on U.S. FDA drug labeling data. 33 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Acetaminophen, Acetazolamide, Articaine. Patients taking Prilocaine Hcl And Epinephrine should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 33
Major: 33

Major (33)

Prilocaine Hcl And Epinephrine + Acetaminophen— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to acetaminophen.
Prilocaine Hcl And Epinephrine + Acetazolamide— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to sulfonamides.
Prilocaine Hcl And Epinephrine + Articaine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to articaine.
Prilocaine Hcl And Epinephrine + Benzocaine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to benzocaine.
Prilocaine Hcl And Epinephrine + Bupivacaine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to bupivacaine.
Prilocaine Hcl And Epinephrine + Chloroquine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to chloroquine.
Prilocaine Hcl And Epinephrine + Cyclophosphamide— Clinically Significant Drug Interactions Patients who are administered local anesthetics are at increased risk of develo…
Prilocaine Hcl And Epinephrine + Dapsone— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to dapsone.
Prilocaine Hcl And Epinephrine + Ergot-Type Oxytocic Drugs— Concurrent administration with vasopressor drugs may cause severe, persistent hypertension or cerebrovascular accidents.
Prilocaine Hcl And Epinephrine + Flutamide— Clinically Significant Drug Interactions Patients who are administered local anesthetics are at increased risk of develo…
Prilocaine Hcl And Epinephrine + Hydroxyurea— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to hydroxyurea.
Prilocaine Hcl And Epinephrine + Ifosfamide— Clinically Significant Drug Interactions Patients who are administered local anesthetics are at increased risk of develo…
Prilocaine Hcl And Epinephrine + Lidocaine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to lidocaine.
Prilocaine Hcl And Epinephrine + Mepivacaine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to mepivacaine.
Prilocaine Hcl And Epinephrine + Metoclopramide— Clinically Significant Drug Interactions Patients who are administered local anesthetics are at increased risk of develo…
Prilocaine Hcl And Epinephrine + Monoamine Oxidase Inhibitors (Maois)— May produce severe, prolonged hypotension or hypertension; concurrent use should generally be avoided.
Prilocaine Hcl And Epinephrine + Nitric Oxide— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to nitric oxide.
Prilocaine Hcl And Epinephrine + Nitrofurantoin— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to nitrofurantoin.
Prilocaine Hcl And Epinephrine + Nitroglycerin— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to nitroglycerin.
Prilocaine Hcl And Epinephrine + Nitroprusside— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to nitroprusside.
Prilocaine Hcl And Epinephrine + Nitrous Oxide— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to nitrous oxide.
Prilocaine Hcl And Epinephrine + Para-Aminosalicylic Acid— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to para-aminosalicylic acid.
Prilocaine Hcl And Epinephrine + Phenobarbital— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to phenobarbital.
Prilocaine Hcl And Epinephrine + Phenothiazines— May produce severe, prolonged hypotension or hypertension; concurrent use should generally be avoided.
Prilocaine Hcl And Epinephrine + Phenytoin— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to phenytoin.
Prilocaine Hcl And Epinephrine + Primaquine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to primaquine.
Prilocaine Hcl And Epinephrine + Procaine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to procaine.
Prilocaine Hcl And Epinephrine + Quinine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to quinine.
Prilocaine Hcl And Epinephrine + Rasburicase— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to rasburicase.
Prilocaine Hcl And Epinephrine + Ropivacaine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to ropivacaine.
Prilocaine Hcl And Epinephrine + Sulfasalazine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to sulfasalazine.
Prilocaine Hcl And Epinephrine + Tetracaine— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to tetracaine.
Prilocaine Hcl And Epinephrine + Valproate Sodium— Increased risk of methemoglobinemia when prilocaine is concurrently exposed to sodium valproate.

Prilocaine Hcl And Epinephrine + Acetaminophen⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to acetaminophen.

Prilocaine Hcl And Epinephrine + Acetazolamide⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to sulfonamides.

Prilocaine Hcl And Epinephrine + Articaine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to articaine.

Prilocaine Hcl And Epinephrine + Benzocaine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to benzocaine.

Prilocaine Hcl And Epinephrine + Bupivacaine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to bupivacaine.

Prilocaine Hcl And Epinephrine + Chloroquine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to chloroquine.

Prilocaine Hcl And Epinephrine + Cyclophosphamide⚠️Major

Clinically Significant Drug Interactions Patients who are administered local anesthetics are at increased risk of developing methemoglobinemia when concurrently exposed to the following drugs, which could include other local anesthetics: EXAMPLES OF DRUGS ASSOCIATED WITH METHEMOGLOBINEMIA: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic Agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine The administration of local anesthetic injections containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants or phenothiazines may produce severe, prolonged hypotension or hypertension.

Prilocaine Hcl And Epinephrine + Dapsone⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to dapsone.

Prilocaine Hcl And Epinephrine + Ergot-Type Oxytocic Drugs⚠️Major

Concurrent administration with vasopressor drugs may cause severe, persistent hypertension or cerebrovascular accidents.

Prilocaine Hcl And Epinephrine + Flutamide⚠️Major

Prilocaine Hcl And Epinephrine + Hydroxyurea⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to hydroxyurea.

Prilocaine Hcl And Epinephrine + Ifosfamide⚠️Major

Prilocaine Hcl And Epinephrine + Lidocaine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to lidocaine.

Prilocaine Hcl And Epinephrine + Mepivacaine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to mepivacaine.

Prilocaine Hcl And Epinephrine + Metoclopramide⚠️Major

Prilocaine Hcl And Epinephrine + Monoamine Oxidase Inhibitors (Maois)⚠️Major

May produce severe, prolonged hypotension or hypertension; concurrent use should generally be avoided.

Prilocaine Hcl And Epinephrine + Nitric Oxide⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to nitric oxide.

Prilocaine Hcl And Epinephrine + Nitrofurantoin⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to nitrofurantoin.

Prilocaine Hcl And Epinephrine + Nitroglycerin⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to nitroglycerin.

Prilocaine Hcl And Epinephrine + Nitroprusside⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to nitroprusside.

Prilocaine Hcl And Epinephrine + Nitrous Oxide⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to nitrous oxide.

Prilocaine Hcl And Epinephrine + Para-Aminosalicylic Acid⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to para-aminosalicylic acid.

Prilocaine Hcl And Epinephrine + Phenobarbital⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to phenobarbital.

Prilocaine Hcl And Epinephrine + Phenothiazines⚠️Major

May produce severe, prolonged hypotension or hypertension; concurrent use should generally be avoided.

Prilocaine Hcl And Epinephrine + Phenytoin⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to phenytoin.

Prilocaine Hcl And Epinephrine + Primaquine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to primaquine.

Prilocaine Hcl And Epinephrine + Procaine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to procaine.

Prilocaine Hcl And Epinephrine + Quinine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to quinine.

Prilocaine Hcl And Epinephrine + Rasburicase⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to rasburicase.

Prilocaine Hcl And Epinephrine + Ropivacaine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to ropivacaine.

Prilocaine Hcl And Epinephrine + Sulfasalazine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to sulfasalazine.

Prilocaine Hcl And Epinephrine + Tetracaine⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to tetracaine.

Prilocaine Hcl And Epinephrine + Valproate Sodium⚠️Major

Increased risk of methemoglobinemia when prilocaine is concurrently exposed to sodium valproate.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.