Maois has 15 known drug interactions based on U.S. FDA drug labeling data. Of these, 10 are contraindicated combinations that should be avoided entirely. 4 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Citalopram Hydrobromide, Dextroamphetamine Saccharate, Amphetamine Aspartate Monohydrate, Dextroamphetamine Sulfate And Amphetamine Sulfate, Doxepin Hydrochloride. Patients taking Maois should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 15
- Contraindicated
- 10
- Major
- 4
- Moderate
- 1
Contraindicated (10)
- Maois + Citalopram Hydrobromide— Contraindicated due to risk of serotonin syndrome. See CONTRAINDICATIONS and WARNINGS sections.
- Maois + Dextroamphetamine Saccharate, Amphetamine Aspartate Monohydrate, Dextroamphetamine Sulfate And Amphetamine Sulfate— Concomitant use can cause hypertensive crisis with potentially fatal outcomes including death, stroke, myocardial infarc…
- Maois + Doxepin Hydrochloride— Doxepin should not be administered in patients on MAOIs within the past two weeks.
- Maois + Escitalopram— Concomitant use with MAOIs is contraindicated. See Dosage and Administration, Contraindications, and Warnings and Precau…
- Maois + Escitalopram Oxalate— Concomitant use with MAOIs is contraindicated due to risk of serotonin syndrome.
- Maois + Tetrabenazine— Tetrabenazine is contraindicated in patients taking MAOIs. Should not be used within minimum of 14 days of discontinuing…
- Maois + Trazodone Hydrochloride— MAOIs should not be used within 14 days of trazodone due to risk of serotonin syndrome.
- Maois + Venlafaxine— Concomitant use is contraindicated. Avoid MAOIs 14 days before starting venlafaxine and 7 days after stopping.
- Maois + Venlafaxine Hcl Er— Concomitant use contraindicated. Avoid MAOIs 14 days before starting venlafaxine and 7 days after stopping venlafaxine.
- Maois + Venlafaxine Hydrochloride— Concomitant use is contraindicated. Avoid MAOIs 14 days before starting venlafaxine and 7 days after stopping.
Major (4)
- Maois + Bupropion— Increased risk of hypertensive reactions when used concomitantly with bupropion.
- Maois + Bupropion Hydrobromide— Increased risk of hypertensive reactions can occur when used concomitantly with bupropion.
- Maois + Bupropion Hydrochloride— Increased risk of hypertensive reactions can occur when used concomitantly with bupropion.
- Maois + Phenobarbital— MAOIs prolong the effects of barbiturates by inhibiting barbiturate metabolism.
Moderate (1)
- Maois + Phenobarbital Sodium— MAOIs prolong the effects of barbiturates by inhibiting barbiturate metabolism.