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Acetaminophen, Caffeine, Dihydrocodeine Bitartrate

Also known as: Trezix

Central Nervous System StimulantMethylxanthine

Route: Oral

Check Acetaminophen, Caffeine, Dihydrocodeine Bitartrate Interactions →
24 interactions on record⛔ Black Box Warning

Acetaminophen, Caffeine, Dihydrocodeine Bitartrate has 24 known drug interactions based on U.S. FDA drug labeling data. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Monoamine Oxidase Inhibitors (Maois), Phenothiazines, Alcohol. Patients taking Acetaminophen, Caffeine, Dihydrocodeine Bitartrate should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total
24
Major
2
Moderate
17
Minor
4

Major (2)

Moderate (17)

Minor (4)

Acetaminophen, Caffeine, Dihydrocodeine Bitartrate + Dihydrocodeineℹ️Unknown

Drug Interactions: Dihydrocodeine with Other Central Nervous System Depressants: Patients receiving other opioid analgesics, sedatives or hypnotics, muscle relaxants, general anesthetics, centrally acting anti-emetics, phenothiazines or other tranquilizers, or alcohol concomitantly with this combination product may exhibit additive depressant effects on the central nervous system. Dihydrocodeine with Monoamine Oxidase Inhibitors: Dihydrocodeine, like all opioid analgesics, interacts with monoamine oxidase inhibitors causing central nervous system excitation and hypertension. Dihydrocodeine with Mixed Agonist/Antagonist Opioid Analgesics: Agonist/antagonist analgesics (i.e., pentazocine, nalbuphine, butorphanol and buprenorphine) may reduce the analgesic effect of this combination product.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.