Ethynodiol Diacetate And Ethinyl Estradiol has 13 known drug interactions based on U.S. FDA drug labeling data. Of these, 2 are contraindicated combinations that should be avoided entirely. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Dasabuvir, Ombitasvir/Paritaprevir/Ritonavir, Rifampin. Patients taking Ethynodiol Diacetate And Ethinyl Estradiol should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 13
- Contraindicated
- 2
- Major
- 2
- Moderate
- 6
Contraindicated (2)
- Ethynodiol Diacetate And Ethinyl Estradiol + Dasabuvir— Do not co-administer with HCV combination therapy containing ombitasvir/paritaprevir/ritonavir due to potential for ALT …
- Ethynodiol Diacetate And Ethinyl Estradiol + Ombitasvir/Paritaprevir/Ritonavir— Do not co-administer due to potential for ALT elevations.
Major (2)
- Ethynodiol Diacetate And Ethinyl Estradiol + Rifampin— Reduced efficacy and increased incidence of breakthrough bleeding and menstrual irregularities with concomitant use.
- Ethynodiol Diacetate And Ethinyl Estradiol + Troglitazone— Reduces plasma concentrations of both hormones by approximately 30%, resulting in loss of contraceptive efficacy.
Moderate (6)
- Ethynodiol Diacetate And Ethinyl Estradiol + Ampicillin— Possible association with reduced contraceptive efficacy, though less marked than rifampin.
- Ethynodiol Diacetate And Ethinyl Estradiol + Barbiturates— Similar association with reduced efficacy, though less marked than rifampin.
- Ethynodiol Diacetate And Ethinyl Estradiol + Griseofulvin— Possible association with reduced contraceptive efficacy, though less marked than rifampin.
- Ethynodiol Diacetate And Ethinyl Estradiol + Phenylbutazone— Similar association with reduced efficacy, though less marked than rifampin.
- Ethynodiol Diacetate And Ethinyl Estradiol + Phenytoin Sodium— Similar association with reduced efficacy, though less marked than rifampin.
- Ethynodiol Diacetate And Ethinyl Estradiol + Tetracycline— Possible association with reduced contraceptive efficacy, though less marked than rifampin.