Estradiol And Norethindrone Acetate has 10 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Carbamazepine, Clarithromycin, Erythromycin. Patients taking Estradiol And Norethindrone Acetate should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 10
- Moderate
- 10
Moderate (10)
- Estradiol And Norethindrone Acetate + Carbamazepine— CYP3A4 inducer that may reduce plasma concentrations of estrogens, possibly decreasing therapeutic effects and/or alteri…
- Estradiol And Norethindrone Acetate + Clarithromycin— CYP3A4 inhibitor that may increase plasma concentrations of estrogens and result in adverse reactions.
- Estradiol And Norethindrone Acetate + Erythromycin— CYP3A4 inhibitor that may increase plasma concentrations of estrogens and result in adverse reactions.
- Estradiol And Norethindrone Acetate + Grapefruit Juice— CYP3A4 inhibitor that may increase plasma concentrations of estrogens and result in adverse reactions.
- Estradiol And Norethindrone Acetate + Itraconazole— CYP3A4 inhibitor that may increase plasma concentrations of estrogens and result in adverse reactions.
- Estradiol And Norethindrone Acetate + Ketoconazole— CYP3A4 inhibitor that may increase plasma concentrations of estrogens and result in adverse reactions.
- Estradiol And Norethindrone Acetate + Phenobarbital— CYP3A4 inducer that may reduce plasma concentrations of estrogens, possibly decreasing therapeutic effects and/or alteri…
- Estradiol And Norethindrone Acetate + Rifampin— CYP3A4 inducer that may reduce plasma concentrations of estrogens, possibly decreasing therapeutic effects and/or alteri…
- Estradiol And Norethindrone Acetate + Ritonavir— CYP3A4 inhibitor that may increase plasma concentrations of estrogens and result in adverse reactions.
- Estradiol And Norethindrone Acetate + St. John'S Wort— CYP3A4 inducer that may reduce plasma concentrations of estrogens, possibly decreasing therapeutic effects and/or alteri…