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Hydrocodone Bitartrate And Ibuprofen

Also known as: Hydrocodone Bitartrate And Ibuprofen

Nonsteroidal Anti-inflammatory DrugCyclooxygenase Inhibitors

Route: Oral

Check Hydrocodone Bitartrate And Ibuprofen Interactions →
12 interactions on record⛔ Black Box Warning

Hydrocodone Bitartrate And Ibuprofen has 12 known drug interactions based on U.S. FDA drug labeling data. 9 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Carbamazepine, Erythromycin, Gabapentin. Patients taking Hydrocodone Bitartrate And Ibuprofen should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total
12
Major
9

Major (9)

Hydrocodone Bitartrate And Ibuprofen + Hydrocodoneℹ️Unknown

Drug Interactions Inhibitors of CYP3A4 and CYP2D6 The concomitant use of hydrocodone bitartrate and ibuprofen tablets and CYP3A4 inhibitors, such as macrolide antibiotics (e.g., erythromycin), azole-antifungal agents (e.g. ketoconazole), protease inhibitors (e.g., ritonavir), can increase the plasma concentration of hydrocodone, resulting in increased or prolonged opioid effects. These effects could be more pronounced with concomitant use of hydrocodone bitartrate and ibuprofen tablets and CYP2D6 and CYP3A4 inhibitors, particularly when an inhibitor is added after a stable dose of hydrocodone bitartrate and ibuprofen tablets are achieved (see WARNINGS: Risks of Concomitant Use or Discontinuation of Cytochrome P450 3A4 Inhibitors and Inducers ).

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.