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Palovarotene

Also known as: Sohonos

Retinoid

Route: Oral

Check Palovarotene Interactions →
4 interactions on record⛔ Black Box Warning

Palovarotene has 4 known drug interactions based on U.S. FDA drug labeling data. Of these, 2 are contraindicated combinations that should be avoided entirely. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Tetracycline, Vitamin A, Cyp3a Inducers. Patients taking Palovarotene should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total
4
Contraindicated
2
Major
2

Contraindicated (2)

  • Palovarotene + Tetracycline— Systemic retinoid use with tetracyclines associated with benign intracranial hypertension cases. Avoid coadministration …
  • Palovarotene + Vitamin A— May cause additive effects. Concomitant administration of vitamin A doses higher than RDA and other oral retinoids must …

Major (2)

  • Palovarotene + Cyp3a Inducers— Co-administration decreases palovarotene exposure, which may reduce effectiveness of SOHONOS. Avoid concomitant use.
  • Palovarotene + Mao Inhibitors— Co-administration increases palovarotene exposure, which may increase risk of adverse reactions. Avoid concomitant use.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.