Colistimethate + Sodium CephalothinContraindicated
May enhance nephrotoxicity of colistimethate; concomitant use should be avoided.
Source: NLP:colistimethate
Colistimethate Interactions
Brand names: Coly-Mycin M
Route: Intramuscular, Intravenous
Contraindications
CONTRAINDICATIONS The use of Coly-Mycin M Parenteral is contraindicated for patients with a history of sensitivity to the drug or any of its components.
Pregnancy & Breastfeeding
Pregnancy - Teratogenic Effects Colistimethate sodium given intramuscularly during organogenesis to rabbits at 4.15 and 9.3 mg/kg resulted in talipes varus in 2.6% and 2.9% of fetuses, respectively. These doses are 0.25 and 0.55 times the maximum daily human dose based on mg/m 2 . In addition, increased resorption occurred at 9.3 mg/kg. Colistimethate sodium was not teratogenic in rats at 4.15 or 9.3 mg/kg. These doses are 0.13 and 0.30 times the maximum daily human dose based on mg/m 2 . There are no adequate and well-controlled studies in pregnant women. Since colistimethate sodium is transferred across the placental barrier in humans, it should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
7 interactions on record
Potentiates neuromuscular blocking effect and should be used with extreme caution in patients being treated with colistimethate.
Source: NLP:colistimethate
Potentiates neuromuscular blocking effect and should be used with extreme caution in patients being treated with colistimethate.
Source: NLP:colistimethate
Polymyxin interferes with nerve transmission at the neuromuscular junction and should not be given concomitantly except with greatest caution.
Source: NLP:colistimethate
Potentiates neuromuscular blocking effect and should be used with extreme caution in patients being treated with colistimethate.
Source: NLP:colistimethate
Potentiates neuromuscular blocking effect and should be used with extreme caution in patients being treated with colistimethate.
Source: NLP:colistimethate
Curariform muscle relaxant that potentiates neuromuscular blocking effect; use with extreme caution in patients treated with colistimethate.
Source: NLP:colistimethate