Adenosine + DigoxinMajor
Rarely associated with ventricular fibrillation when combined with adenosine injection. Use with caution due to potential additive depressant effects on SA and AV nodes.
Source: NLP:adenosine
Adenosine Interactions
Brand names: Adenosine
Adenosine Receptor Agonist · Adenosine Receptor Agonists
Route: Intravenous
Contraindications
CONTRAINDICATIONS Adenosine injection is contraindicated in: 1. Second- or third-degree A-V block (except in patients with a functioning artificial pacemaker). 2. Sinus node disease, such as sick sinus syndrome or symptomatic bradycardia (except in patients with a functioning artificial pacemaker). 3. Known hypersensitivity to adenosine.
Pregnancy & Breastfeeding
Pregnancy Teratogenic Effects: Pregnancy Category C Animal reproduction studies have not been conducted with adenosine; nor have studies been performed in pregnant women. As adenosine is a naturally occurring material, widely dispersed throughout the body, no fetal effects would be anticipated. However, since it is not known whether adenosine can cause fetal harm when administered to pregnant women, adenosine should be used during pregnancy only if clearly needed.
12 interactions on record
Dipyridamole increases plasma levels and cardiovascular effects of adenosine. Adjustment of adenosine dosage may be necessary.
Source: NLP:dipyridamole
Rarely associated with ventricular fibrillation when combined with adenosine injection. Use with caution due to potential additive depressant effects on SA and AV nodes.
Source: NLP:adenosine
Adenosine + AminophyllineModerate
Theophylline blocks adenosine receptors, requiring higher doses of adenosine to achieve therapeutic effect.
Source: NLP:aminophylline
Dipyridamole increases plasma levels and cardiovascular effects of adenosine. Adjustment of adenosine dosage may be necessary.
Source: NLP:aspirin and dipyridamole
Dipyridamole increases plasma levels and cardiovascular effects of adenosine. Adjustment of adenosine dosage may be necessary.
Source: NLP:aspirin and extended-release dipyridamole
Adenosine + CaffeineModerate
Antagonizes the effects of adenosine, potentially reducing efficacy. Larger doses of adenosine may be required.
Source: NLP:adenosine
Given with adenosine without apparent adverse interactions, but adenosine should be used with caution due to potential additive depressant effects on SA and AV nodes.
Source: NLP:adenosine
Adenosine + CarbamazepineModerate
Increases the degree of heart block produced by adenosine, potentially resulting in higher degrees of AV node block.
Source: NLP:adenosine
Adenosine + Cardiac GlycosidesModerate
Given with adenosine without apparent adverse interactions, but adenosine should be used with caution due to potential additive depressant effects on SA and AV nodes.
Source: NLP:adenosine
Given with adenosine without apparent adverse interactions, but adenosine should be used with caution due to potential additive depressant effects on SA and AV nodes.
Source: NLP:adenosine
Adenosine + TheophyllineModerate
Theophylline blocks adenosine receptors, potentially reducing adenosine's therapeutic effects.
Source: NLP:theophylline