Ofloxacin Ophthalmic Solution Usp, 0.3% has 5 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Warfarin, Caffeine, Cyclosporine. Patients taking Ofloxacin Ophthalmic Solution Usp, 0.3% should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 5
- Major
- 1
- Moderate
- 3
Major (1)
- Ofloxacin Ophthalmic Solution Usp, 0.3% + Warfarin— Systemic quinolone administration enhances the effects of oral anticoagulant warfarin and its derivatives.
Moderate (3)
- Ofloxacin Ophthalmic Solution Usp, 0.3% + Caffeine— Systemic quinolone administration interferes with the metabolism of caffeine.
- Ofloxacin Ophthalmic Solution Usp, 0.3% + Cyclosporine— Concomitant systemic quinolone administration is associated with transient elevations in serum creatinine.
- Ofloxacin Ophthalmic Solution Usp, 0.3% + Theophylline— Systemic quinolone administration has been shown to elevate plasma concentrations of theophylline.