Dihydroergotamine Interactions

Do not use almotriptan malate and dihydroergotamine within 24 hours of each other due to risk of prolonged vasospastic reactions.

Source: NLP:almotriptan malate

Ergot-containing drugs cause prolonged vasospastic reactions. Use within 24 hours of eletriptan hydrobromide is contraindicated due to additive effects.

Source: NLP:eletriptan hydrobromide

Co-administration associated with acute ergot toxicity characterized by vasospasm and ischemia of extremities and other tissues including central nervous system.

Source: NLP:erythromycin

Coadministration associated with acute ergot toxicity characterized by vasospasm and ischemia of extremities and central nervous system.

Source: NLP:erythromycin ethylsuccinate

Co-administration associated with acute ergot toxicity characterized by vasospasm and ischemia of central nervous system and tissues.

Source: NLP:erythromycin lactobionate

Coadministration is contraindicated. Itraconazole increases plasma concentrations of ergot alkaloids, potentially increasing pharmacologic effects and adverse reactions.

Source: NLP:itraconazole

Coadministration of ketoconazole with dihydroergotamine is contraindicated.

Source: NLP:ketoconazole

Mifepristone increases dihydroergotamine exposure; concomitant use is contraindicated due to narrow therapeutic range.

Source: NLP:mifepristone

Ergot-type medication causing prolonged vasospastic reactions. Use within 24 hours of rizatriptan benzoate is contraindicated due to potentially additive vasospastic effects.

Source: NLP:rizatriptan benzoate

Ergot-type medication causing prolonged vasospastic reactions with additive effects. Use within 24 hours of sumatriptan is contraindicated.

Source: NLP:sumatriptan

Ergot-type medication causing prolonged vasospastic reactions; additive effects contraindicate use within 24 hours of sumatriptan succinate.

Source: NLP:sumatriptan succinate

Ergot-type medication causing prolonged vasospastic reactions. Coadministration within 24 hours is contraindicated due to additive effects.

Source: NLP:sumatriptan and naproxen sodium

Ergot-type medication causing prolonged vasospastic reactions. Use within 24 hours of zolmitriptan is contraindicated.

Source: NLP:zolmitriptan

Increases risk of hypertension when used concomitantly with midodrine. Avoid concomitant use or monitor blood pressure closely.

Source: NLP:midodrine hydrochloride

Oral nitroglycerin markedly decreases first-pass metabolism and increases bioavailability of dihydroergotamine; monitor for ergotism symptoms.

Source: NLP:nitroglycerin

Deferasirox may induce CYP3A4 resulting in decreased dihydroergotamine concentration. Monitor for reduced effectiveness.

Source: NLP:deferasirox

Oral nitroglycerin markedly decreases first-pass metabolism and increases oral bioavailability. Related to ergotamine; monitor for symptoms of ergotism.

Source: NLP:nitroglycerin lingual