Dihydroergotamine + Erythromycin Ethylsuccinate Interaction

Contraindicatedinteraction on record

Description

Coadministration associated with acute ergot toxicity characterized by vasospasm and ischemia of extremities and central nervous system.

Mechanism

CYP3A inhibition increases dihydroergotamine levels

Source: NLP:erythromycin ethylsuccinate