Sodium Bicarbonate + DobutamineContraindicated
Incompatible with sodium bicarbonate solution; do not combine.
Source: NLP:sodium bicarbonate
Sodium Bicarbonate Interactions
Brand names: Sodium Bicarbonate
Route: Intravenous
Contraindications
CONTRAINDICATIONS Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction, and in patients receiving diuretics known to produce a hypochloremic alkalosis.
Pregnancy & Breastfeeding
Pregnancy: Teratogenic Effects Animal reproduction studies have not been conducted with sodium bicarbonate. It is also not known whether sodium bicarbonate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Sodium bicarbonate should be given to a pregnant woman only if clearly needed.
17 interactions on record
Sodium Bicarbonate + NorepinephrineContraindicated
Incompatible with sodium bicarbonate solution; do not combine.
Source: NLP:sodium bicarbonate
Concurrent use with acetazolamide increases the risk of renal calculus formation.
Source: NLP:acetazolamide
Addition of sodium bicarbonate to parenteral solutions containing calcium should be avoided; precipitation or haze may result from sodium bicarbonate/calcium admixtures.
Source: NLP:sodium bicarbonate
Gastrointestinal alkalinizing agent that increases blood levels and potentiates amphetamine action. Co-administration should be avoided.
Source: NLP:dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, and amphetamine sulfate
Gastrointestinal alkalinizing agent increases blood levels and potentiates amphetamine action. Concomitant use should be avoided.
Source: NLP:dextroamphetamine sulfate
Acetazolamide and sodium bicarbonate used concurrently increase the risk of renal calculus formation.
Source: NLP:acetazolamide extended-release
Gastrointestinal alkalinizing agent that increases amphetamine absorption and potentiates action.
Source: NLP:amphetamine sulfate
High doses reduce peak plasma levels by 24-42% and extent of absorption by 27-32%, but do not alter absorption rate.
Source: NLP:cefpodoxime proxetil
Gastrointestinal alkalinizing agent increases amphetamine absorption, raising blood levels and potentiating actions.
Source: NLP:dextroamphetamine
Lowers serum lithium concentrations by increasing urinary lithium excretion; monitor lithium levels.
Source: NLP:lithium carbonate
Sodium Bicarbonate + MemantineModerate
Sodium bicarbonate alters urine pH towards alkaline conditions, reducing memantine clearance by about 80% and potentially leading to drug accumulation and increased adverse effects.
Source: NLP:memantine
Sodium bicarbonate alters urine pH towards alkaline conditions, which may reduce memantine clearance by about 80% and lead to drug accumulation and increased adverse effects.
Source: NLP:memantine hydrochloride oral
Sodium bicarbonate may alter urine pH towards alkaline conditions, reducing memantine clearance by about 80% and leading to drug accumulation.
Source: NLP:memantine hydrochloride and donepezil hydrochloride
Sodium bicarbonate alkalinizes urine and reduces renal elimination of quinidine.
Source: NLP:quinidine gluconate
Alkalinizes urine and reduces renal elimination of quinidine, increasing quinidine levels.
Source: NLP:quinidine sulfate tablet
Sodium bicarbonate impairs absorption of tetracycline.
Source: NLP:tetracycline hydrochloride