Triamterene Capsules has 8 known drug interactions based on U.S. FDA drug labeling data. 4 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Chlorpropamide, Indomethacin, Lithium. Patients taking Triamterene Capsules should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 8
- Major
- 4
- Moderate
- 3
Major (4)
- Triamterene Capsules + Chlorpropamide— Triamterene may raise blood glucose levels; for adult-onset diabetes, dosage adjustments of hypoglycemic agents may be n…
- Triamterene Capsules + Indomethacin— Acute renal failure has been reported when indomethacin was given with triamterene. Caution is advised.
- Triamterene Capsules + Lithium— Diuretic-induced sodium loss may reduce renal clearance of lithium and increase serum lithium levels with risk of lithiu…
- Triamterene Capsules + Mao Inhibitors— Potassium-sparing agents used with ACE inhibitors increase risk of hyperkalemia.
Moderate (3)
- Triamterene Capsules + Muscle Relaxants— Non-depolarizing skeletal muscle relaxants effects may be potentiated when given together with triamterene.
- Triamterene Capsules + Other Anticholinergic Agents— Effects may be potentiated when given together with triamterene.
- Triamterene Capsules + Topical Local Anesthetics— Effects may be potentiated when given together with triamterene.