Trospium Chloride has 8 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Metformin, Morphine, Pancuronium. Patients taking Trospium Chloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 8
- Moderate
- 6
- Minor
- 1
Moderate (6)
- Trospium Chloride + Metformin— Co-administration reduced steady-state systemic exposure of trospium by approximately 29% for AUC and 34% for Cmax; effe…
- Trospium Chloride + Morphine— May increase serum concentration of trospium and/or morphine due to competition for renal tubular secretion. Careful pat…
- Trospium Chloride + Pancuronium— May increase serum concentration of trospium and/or pancuronium due to competition for renal tubular secretion. Careful …
- Trospium Chloride + Procainamide— May increase serum concentration of trospium and/or procainamide due to competition for renal tubular secretion. Careful…
- Trospium Chloride + Tenofovir— May increase serum concentration of trospium and/or tenofovir due to competition for renal tubular secretion. Careful pa…
- Trospium Chloride + Vancomycin— May increase serum concentration of trospium and/or vancomycin due to competition for renal tubular secretion. Careful p…
Minor (1)
- Trospium Chloride + Digoxin— Concomitant use did not affect the pharmacokinetics of either drug.