Methacholine Chloride has 8 known drug interactions based on U.S. FDA drug labeling data. 6 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Albuterol, Ipratropium, Nonselective Beta-Adrenergic Antagonists. Patients taking Methacholine Chloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 8
- Major
- 6
- Moderate
- 2
Major (6)
- Methacholine Chloride + Albuterol— Inhibits airway response to methacholine chloride; hold for 6 hours before testing.
- Methacholine Chloride + Ipratropium— Inhibits airway response to methacholine chloride; hold for 12 hours before testing.
- Methacholine Chloride + Nonselective Beta-Adrenergic Antagonists— May impair reversal of methacholine chloride-caused bronchoconstriction.
- Methacholine Chloride + Salmeterol— Inhibits airway response to methacholine chloride; hold for 36 hours before testing.
- Methacholine Chloride + Theophylline— Inhibits airway response to methacholine chloride; hold for 12-48 hours before testing.
- Methacholine Chloride + Tiotropium— Inhibits airway response to methacholine chloride; hold for ≥168 hours before testing.
Moderate (2)
- Methacholine Chloride + Corticosteroids— Regular use may acutely decrease bronchial responsiveness to methacholine chloride; may be continued during testing.
- Methacholine Chloride + Inhaled Cromoglycate— Regular use may acutely decrease bronchial responsiveness to methacholine chloride; may be continued during testing.