Ergot Alkaloids has 15 known drug interactions based on U.S. FDA drug labeling data. Of these, 1 are contraindicated combinations that should be avoided entirely. 10 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Bromocriptine Mesylate, Adrenalin (Epinephrine), Albuterol Sulfate. Patients taking Ergot Alkaloids should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 15
- Contraindicated
- 1
- Major
- 10
- Moderate
- 4
Contraindicated (1)
- Ergot Alkaloids + Bromocriptine Mesylate— Concomitant use of bromocriptine with other ergot alkaloids is not recommended.
Major (10)
- Ergot Alkaloids + Adrenalin (Epinephrine)— Ergot alkaloids may reverse the pressor effects of epinephrine.
- Ergot Alkaloids + Albuterol Sulfate— Ergot alkaloids may reverse the pressor effects of epinephrine.
- Ergot Alkaloids + Epinephrine— Ergot alkaloids may reverse the pressor effects of epinephrine.
- Ergot Alkaloids + Epinephrine 0.15 Pediatrics— Ergot alkaloids may reverse the pressor effects of epinephrine.
- Ergot Alkaloids + Epinephrine 0.3 Adults— Ergot alkaloids may reverse the pressor effects of epinephrine.
- Ergot Alkaloids + Metoprolol Tartrate— Concomitant administration with metoprolol may enhance the vasoconstrictive action of ergot alkaloids.
- Ergot Alkaloids + Minocycline Hydrochloride— Increased risk of ergotism when ergot alkaloids are given with tetracyclines.
- Ergot Alkaloids + Phenylephrine Hydrochloride— Agonistic effects increase phenylephrine blood pressure effect.
- Ergot Alkaloids + Promethazine Hydrochloride And Phenylephrine Hydrochloride— Phenylephrine with ergot alkaloids causes excessive rise in blood pressure.
- Ergot Alkaloids + Promethazine, Phenylephrine, Codeine— Concomitant use may enhance the pressor response and increase the risk of hypertension.
Moderate (4)
- Ergot Alkaloids + Auvi-Q— May reverse the pressor effects of epinephrine.
- Ergot Alkaloids + Epinephrine In Sodium Chloride— Counter the pressor effects of epinephrine.
- Ergot Alkaloids + Metoprolol— Concomitant administration with metoprolol may enhance vasoconstrictive action of ergot alkaloids.
- Ergot Alkaloids + Miconazole— Potential interaction with ergot alkaloids metabolized through CYP2C9 and CYP3A4 cannot be ruled out due to miconazole's…