Trimetrexate + SepiapterinContraindicated
DHFR inhibitor that may reduce sepiapterin metabolism to tetrahydrobiopterin (BH4). Avoid concomitant use.
Source: NLP:sepiapterin
Trimetrexate Interactions
2 interactions on record
Trimetrexate + ItraconazoleModerate
Itraconazole increases trimetrexate concentrations. Monitor for adverse reactions; dose reduction may be necessary.
Source: NLP:itraconazole