Gastric Ph Modulators (H2-Blockers, Proton Pump Inhibitors) has 3 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Methylphenidate, Dextroamphetamine Saccharate, Amphetamine Aspartate Monohydrate, Dextroamphetamine Sulfate And Amphetamine Sulfate, Dolutegravir Sodium And Rilpivirine Hydrochloride. Patients taking Gastric Ph Modulators (H2-Blockers, Proton Pump Inhibitors) should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 3
- Major
- 1
- Moderate
- 2
Major (1)
- Gastric Ph Modulators (H2-Blockers, Proton Pump Inhibitors) + Methylphenidate— May change the release profile and alter the pharmacodynamics of methylphenidate. Concomitant use is not recommended.
Moderate (2)
- Gastric Ph Modulators (H2-Blockers, Proton Pump Inhibitors) + Dextroamphetamine Saccharate, Amphetamine Aspartate Monohydrate, Dextroamphetamine Sulfate And Amphetamine Sulfate— Potential change in pharmacokinetic profile and exposure may occur. Monitor for changes in clinical effect.
- Gastric Ph Modulators (H2-Blockers, Proton Pump Inhibitors) + Dolutegravir Sodium And Rilpivirine Hydrochloride— Drugs increasing gastric pH may decrease plasma concentrations of dolutegravir and rilpivirine. Monitor virologic respon…