Hyaluronidase, Ovine has 11 known drug interactions based on U.S. FDA drug labeling data. Of these, 5 are contraindicated combinations that should be avoided entirely. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Alpha-Blockers, Dopamine Agonists, Furosemide. Patients taking Hyaluronidase, Ovine should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 11
- Contraindicated
- 5
- Major
- 1
- Moderate
- 5
Contraindicated (5)
- Hyaluronidase, Ovine + Alpha-Blockers— Hyaluronidase should not be used to enhance absorption and dispersion of alpha agonist drugs.
- Hyaluronidase, Ovine + Dopamine Agonists— Hyaluronidase should not be used to enhance absorption and dispersion of dopamine.
- Hyaluronidase, Ovine + Furosemide— Incompatible with hyaluronidase; physical or chemical incompatibility reported.
- Hyaluronidase, Ovine + Nitrazepam— Incompatible with hyaluronidase; physical or chemical incompatibility reported.
- Hyaluronidase, Ovine + Phenytoin— Incompatible with hyaluronidase; physical or chemical incompatibility reported.
Major (1)
- Hyaluronidase, Ovine + Topical Local Anesthetics— Hyaluronidase hastens onset and shortens duration of effect; increases incidence of systemic reactions due to wider spre…
Moderate (5)
- Hyaluronidase, Ovine + Antihistamines— Large doses may require larger amounts of hyaluronidase for equivalent dispersing effect; tissues become partly resistan…
- Hyaluronidase, Ovine + Cortisone— Large doses may require larger amounts of hyaluronidase for equivalent dispersing effect; tissues become partly resistan…
- Hyaluronidase, Ovine + Estrogens— Large doses may require larger amounts of hyaluronidase for equivalent dispersing effect; tissues become partly resistan…
- Hyaluronidase, Ovine + Repository Corticotropin— Large doses may require larger amounts of hyaluronidase for equivalent dispersing effect; tissues become partly resistan…
- Hyaluronidase, Ovine + Salicylates— Large doses may require larger amounts of hyaluronidase for equivalent dispersing effect; tissues become partly resistan…