Halofantrine has 3 known drug interactions based on U.S. FDA drug labeling data. Of these, 3 are contraindicated combinations that should be avoided entirely. Notable interactions include combinations with Mefloquine Hydrochloride, Pimozide, Quinine Sulfate. Patients taking Halofantrine should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 3
- Contraindicated
- 3
Contraindicated (3)
- Halofantrine + Mefloquine Hydrochloride— Should not be administered with mefloquine or within 15 weeks of last mefloquine dose due to risk of potentially fatal Q…
- Halofantrine + Pimozide— Additive QT interval prolongation effect anticipated, increasing risk of ventricular arrhythmias.
- Halofantrine + Quinine Sulfate— Other antimalarial causing ECG abnormalities including QT prolongation when combined with quinine sulfate.