Insulin Aspart Injection has 38 known drug interactions based on U.S. FDA drug labeling data. 6 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Disopyramide, Fluoxetine, Octreotide. Patients taking Insulin Aspart Injection should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 38
- Major
- 6
- Moderate
- 30
Major (6)
- Insulin Aspart Injection + Disopyramide— May increase the risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Fluoxetine— May increase the risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Octreotide— Somatostatin analog that may increase the risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be …
- Insulin Aspart Injection + Pentamidine— May cause hypoglycemia sometimes followed by hyperglycemia. Dose adjustment and glucose monitoring may be required.
- Insulin Aspart Injection + Pentoxifylline— May increase the risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Pramlintide— May increase the risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be required.
Moderate (30)
- Insulin Aspart Injection + Acidifying Agents— May increase risk of hypoglycemia. Dose reductions and increased glucose monitoring may be required.
- Insulin Aspart Injection + Albuterol— Sympathomimetic agent that may decrease the blood glucose lowering effect. Dose adjustment and increased glucose monitor…
- Insulin Aspart Injection + Alcohol— May increase or decrease the blood glucose lowering effect. Dose adjustment and increased glucose monitoring required.
- Insulin Aspart Injection + Angiotensin Ii— May increase risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Clonidine— May increase or decrease the blood glucose lowering effect and blunt signs/symptoms of hypoglycemia. Increased glucose m…
- Insulin Aspart Injection + Clozapine— Atypical antipsychotic that may decrease the blood glucose lowering effect. Dose adjustment and increased glucose monito…
- Insulin Aspart Injection + Corticosteroids— May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Danazol— May decrease the blood glucose lowering effect. Dose adjustment and increased glucose monitoring required.
- Insulin Aspart Injection + Diuretics— May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Epinephrine— Sympathomimetic agent that may decrease the blood glucose lowering effect. Dose adjustment and increased glucose monitor…
- Insulin Aspart Injection + Estrogens— May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Fibrates— May increase risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Glucagon— May decrease the blood glucose lowering effect. Dose adjustment and increased glucose monitoring required.
- Insulin Aspart Injection + Guanethidine— May blunt signs and symptoms of hypoglycemia. Increased frequency of glucose monitoring required.
- Insulin Aspart Injection + Isoniazid— May decrease the blood glucose lowering effect. Dose adjustment and increased glucose monitoring required.
- Insulin Aspart Injection + Lithium— May increase or decrease the blood glucose lowering effect. Dose adjustment and increased glucose monitoring required.
- Insulin Aspart Injection + Macrolide Antibiotics— May increase risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Mao Inhibitors— May increase risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Monoamine Oxidase Inhibitors (Maois)— May increase risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Niacin— May decrease the blood glucose lowering effect. Dose adjustment and increased glucose monitoring required.
- Insulin Aspart Injection + Nonselective Beta-Adrenergic Antagonists— May increase or decrease blood glucose lowering effect and may blunt signs/symptoms of hypoglycemia. Increased glucose m…
- Insulin Aspart Injection + Olanzapine— Atypical antipsychotic that may decrease the blood glucose lowering effect. Dose adjustment and increased glucose monito…
- Insulin Aspart Injection + Oral Contraceptives— May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Phenothiazines— May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Protease Inhibitors— May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Reserpine— May blunt signs and symptoms of hypoglycemia. Increased frequency of glucose monitoring required.
- Insulin Aspart Injection + Salicylates— May increase risk of hypoglycemia. Dose adjustment and increased glucose monitoring may be required.
- Insulin Aspart Injection + Somatropin— May decrease the blood glucose lowering effect. Dose adjustment and increased glucose monitoring required.
- Insulin Aspart Injection + Terbutaline— Sympathomimetic agent that may decrease the blood glucose lowering effect. Dose adjustment and increased glucose monitor…
- Insulin Aspart Injection + Thyroid Hormones— May decrease blood glucose lowering effect. Dose adjustment and increased glucose monitoring may be required.